Australia's mesothelioma guidelines have been updated, reflecting major advances in pathology, immunotherapy, and multidisciplinary care. The new recommendations aim to establish a nationally consistent standard of care for pleural mesothelioma, a disease disproportionately affecting Australians due to decades of widespread asbestos use. The guidelines emphasize reducing delays in diagnosis, incorporating modern immunohistochemistry and molecular testing, and integrating palliative care from diagnosis. They also address inequities in care by expanding telehealth and virtual multidisciplinary meetings for patients in regional and remote areas. The document highlights the importance of legal advice for mesothelioma patients, recognizing the rarity of the disease and the need for continued research and education to improve patient outcomes.